Elongation factor 1 gamma mRNA expression in oesophageal carcinoma.
نویسندگان
چکیده
منابع مشابه
Biophysical characterisation of human eukaryotic elongation factor 1 Beta and its interaction with human eukaryotic elongation factor 1 Gamma
............................................................................................................................... iv Acknowledgements ................................................................................................................ v List of abbreviations ........................................................................................................... viii...
متن کاملTranscription elongation factor hSPT5 stimulates mRNA capping.
RNA polymerase II nascent transcripts are capped during pausing before elongation. Here we report that hSPT5, the human homolog of yeast elongation factor SPT5, interacts directly with the capping enzyme. hSPT5 stimulated capping enzyme guanylylation and mRNA capping by severalfold. Although RNA 5'-triphosphatase activity was unaffected, binding to this domain in the full-length enzyme is likel...
متن کاملA homologue of elongation factor 1 gamma regulates methionine sulfoxide reductase A gene expression in Saccharomyces cerevisiae.
Methionine sulfoxide reductase A (MsrA) maintains the function of many proteins by reversing oxidation of methionine residues. Lack of this repair mechanism very likely increases aging-related disease susceptibility. In Saccharomyces cerevisiae, disruption of the msrA gene increases free and protein-bound methionine sulfoxide and decreases cell viability. Although the underlying mechanisms in t...
متن کاملInteractions of Elongation Factor 1 with F-Actin and -Actin mRNA: Implications for Anchoring mRNA in Cell Protrusions
The targeting of mRNA and local protein synthesis is important for the generation and maintenance of cell polarity. As part of the translational machinery as well as an actin/ microtubule-binding protein, elongation factor 1 (EF1 ) is a candidate linker between the protein translation apparatus and the cytoskeleton. We demonstrate in this work that EF1 colocalizes with -actin mRNA and F-actin i...
متن کاملOesophageal tuberculosis mimicking oesophageal carcinoma.
Tuberculous involvement of the oesophagus is rare, and is usually caused by direct spread from adjacent afflicted structures. We report an 83-year-old male patient with oesophageal tuberculosis secondary to tuberculous mediastinal lymphadenitis who presented with non-specific symptoms of anorexia and lethargy. Upper gastro-intestinal endoscopy revealed an ulcerative tumour-like lesion in the mi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gut
سال: 1996
ISSN: 0017-5749
DOI: 10.1136/gut.38.1.66